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Article

Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells.

International journal of molecular sciences - 20 Nov 2020

Badran Adnan, Nasser Suzanne A, Mesmar Joelle, El-Yazbi Ahmed F, Bitto Alessandra, Fardoun Manal M, Baydoun Elias, Eid Ali H

Abstract excerpt

Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling. However, high ROS levels cause oxidative stress, which is implicated in cardiovascular diseases (CVD) such as atherosclerosis, hypertension, and restenosis after angioplasty. Despite the great amount of research conducted to identify the role of ROS in CVD, the...

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Identifiers

PMID: 33233489
DOI: 10.3390/ijms21228764
PMCID: PMC7699590

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