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Integrative analysis reveals generalizable human neurodegenerative disease-associated glial states

2025-09-25

Abstract excerpt

Glial cells are known to respond transcriptionally in multiple neurodegenerative diseases (NDDs). In particular, microglial states have been characterized in Alzheimer’s disease and mouse models of amyloidosis as disease-associated microglia. Although single-cell transcriptomic technologies have increased the dimensionality of information available across cell states, few studies have systematically tested for cha...

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Literature Corpus work
82d633f2-e6e8-586f-bf20-8572fb27485f
DOI
10.1101/2025.09.25.678630
Open publication

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Integrative analysis reveals generalizable human neurodegenerative disease-associated glial statesDOI 10.1101/2025.09.25.678630
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