Article

The Impact of Oxytocin on Neurite Outgrowth and Synaptic Proteins in <i>Magel2</i> -Deficient Mice

2020-09-24

Abstract excerpt

Oxytocin contributes to the regulation of cytoskeletal and synaptic proteins and could therefore affect the mechanisms of neurodevelopmental disorders, including autism. Both the Prader-Willi syndrome and Schaaf-Yang syndrome exhibit autistic symptoms involving the MAGEL2 gene. Magel2 -deficient mice show a deficit in social behavior that is rescued following postnatal administration of oxytocin. Here, in Magel...

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Literature Corpus work: 82d5eb4d-6208-5668-b3f1-b531a36a47b2
DOI: 10.1101/2020.09.23.309955

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