Article

GPRIN1 modulates neuronal signal transduction and affects mouse-learning behavior

2018-03-30

Abstract excerpt

<h4>ABSTRACT</h4> In the adult and developing brain, G protein-regulated inducer of neurite outgrowth 1 (GPRIN1) is a downstream effector for Gα o/i/z proteins that promotes neurite outgrowth. However, so far, the physiological role of GPRIN1 in brain health has not been reported. We generated a viable GPRIN1 whole-body knockout mouse to assess its physiological role in synaptic function both ex vivo and in vi...

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Literature Corpus work: 8b2497ce-f263-52cc-b324-82e96c2aae27
DOI: 10.1101/291377

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