Article
The distribution of neuroligin4, an autism-related postsynaptic molecule, in the human brain.
Molecular brain - 6 Feb 2023
Toya Akie, Fukada Masahide, Aoki Eiko, Matsuki Tohru, Ueda Masashi, Eda Shima, Hashizume Yoshio, Iio Akio, Masaki Shigeo, Nakayama Atsuo
Abstract excerpt
NLGN4X was identified as a single causative gene of rare familial nonsyndromic autism for the first time. It encodes the postsynaptic membrane protein Neuroligin4 (NLGN4), the functions and roles of which, however, are not fully understood due to the lack of a closely homologous gene in rodents. It has been confirmed only recently that human NLGN4 is abundantly expressed in the cerebral cortex and is localized...
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