Article

Rapid effects of valproic acid on the fetal brain transcriptome: Implications for brain development and autism

2024-01-10

Abstract excerpt

<title>Abstract</title> <p>There is an increased incidence of autism among the children of women who take the anti-epileptic, mood-stabilizing drug, valproic acid (VPA) during pregnancy; moreover, exposure to VPA in utero causes autistic-like symptoms in rodents and non-human primates. Analysis of RNA-seq data obtained from E12.5 fetal mouse brains 3 hours after VPA administration to the pregnant dam revealed tha...

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Literature Corpus work: 670f9351-640c-5204-a349-b13df5515b6b
DOI: 10.21203/rs.3.rs-3684653/v1

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