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DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory sensory epithelium

20 Nov 2018

Abstract excerpt

The inner ear is a complex structure responsible for hearing and balance, and organ pathology is associated with deafness and balance disorders. To evaluate the role of epigenomic dynamics, we performed whole genome bisulfite sequencing at key time points during the development and maturation of the mouse inner ear sensory epithelium (SE). Our single-nucleotide resolution maps revealed variations in both general...

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PMID: 30478432
DOI: 10.1038/s41598-018-35587-x

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