Article

Derivation of Genetically-Defined Murine Hepatoblastoma Cell Lines with Angiogenic Potential

2025-08-03

Abstract excerpt

<h4>Background/Objectives</h4> Hepatoblastoma (HB) is the most common form of pediatric liver cancer, with the vast majority of these tumors evidence of mutation and/or deregulation of the oncogenic transcription factors β-catenin (B), YAP (Y) and NRF2 (N). HB research has been hampered by a paucity of established cell lines, particularly those bearing these molecular drivers. All combinations of B, Y and N (i.e....

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Identifiers and source

Literature Corpus work: 828ab356-6197-5b32-9f79-448df4785be3
DOI: 10.1101/2025.07.25.666764

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