Article

A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis

2021-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Rationale</h4> Hepatoblastoma (HB) is the most common pediatric liver cancer. Its predominant occurrence in very young children led us to investigating whether the neonatal liver provides a protumorigenic niche to HB development. <h4>Methods</h4> HB development was compared between orthotopic transplantation models established in postnatal day 5 and 60 mice (P5 Tx and P60...

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Literature Corpus work: 996f70a2-ed19-5df8-bb6e-693c365b350f
DOI: 10.1101/2021.10.22.465518

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