Article

Establishment of two novel organoid lines from patients with combined hepatocellular cholangiocarcinoma

2024-10-16

Abstract excerpt

<title>Abstract</title> <p>Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a unique subtype of primary liver cancer displaying both hepatocytic and cholangiocytic differentiation. The development of effective treatments for cHCC-CCA remains challenging because of its high heterogeneity and lack of a suitable model system. Using a three-dimensional culture system, we successfully established two novel cHC...

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Literature Corpus work: 668f218f-359a-591e-a97e-6d9dadf16423
DOI: 10.21203/rs.3.rs-4935983/v1

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