Article

Interferon-γ signaling in eosinophilic esophagitis has implications for epithelial barrier function and programmed cell death

2024-01-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Eosinophilic esophagitis (EoE) is a chronic esophageal inflammatory disorder characterized by eosinophil-rich mucosal inflammation and tissue remodeling. Transcriptional profiling of esophageal biopsies has previously revealed upregulation of type I and II interferon (IFN) response genes. We aim to unravel interactions between immune and epithelial cells and examine functiona...

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Literature Corpus work: 824248bc-6a77-58f7-b204-b2577fbb62af
DOI: 10.1101/2024.01.26.577407

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