Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids

30 Dec 2020

Abstract excerpt

Human intestinal organoids (HIOs) are increasingly being used to model intestinal responses to various stimuli, yet few studies have confirmed the fidelity of this modeling system. Given that the interferon-gamma (IFN-γ) response has been well characterized in various other cell types, our goal was to characterize the response to IFN-γ in HIOs derived from induced pluripotent stem cells (iPSCs). To achieve this,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Digestive system and related health
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33396621
DOI: 10.3390/ijms22010288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal OrganoidsPMID 33396621Read ↗

Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem CellsSemantic proximity Read ↗

Establishment of an ulcerative colitis model using colon organoids derived from human induced pluripotent stem cellsSemantic proximity Read ↗

Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBDSemantic proximity Read ↗

Insights into Modeling Inflammatory Bowel Disease from Stem Cell Derived Intestinal OrganoidsSemantic proximity Read ↗

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial BarrierSemantic proximity Read ↗

Transcriptional and Cytotoxic Responses of Human Intestinal Organoids to Interferon Types I, II, and IIISemantic proximity Read ↗

IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migrationSemantic proximity Read ↗

Celiac disease patient derived iPSC–small intestinal epithelial cells are more persistent under cytokine stimuli than healthy control cellsSemantic proximity Read ↗

Human Pluripotent Stem Cell Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory ResponseSemantic proximity Read ↗

A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial OrganoidsSemantic proximity Read ↗

Stem cell-derived intestinal organoids: a novel modality for IBDSemantic proximity Read ↗

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.