Article

FOXM1 Modulation Alleviates Epithelial Remodeling and Inflammation in Eosinophilic Esophagitis

2025-05-28

Abstract excerpt

<h4>Background</h4> Eosinophilic esophagitis (EoE) is a chronic allergic disease characterized by esophageal epithelial remodeling, barrier dysfunction, and inflammation. Despite histologic remission, molecular and structural changes in the epithelium persist, contributing to ongoing symptoms and relapse. The transcription factor FOXM1 has been shown to be a key regulator of epithelial proliferation and inflammat...

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Literature Corpus work: 1843bd3b-7a16-5147-b8c2-259579153126
DOI: 10.1101/2025.05.25.655133

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