A synthesis and subgroup analysis of the eosinophilic esophagitis tissue transcriptome

Abstract excerpt

BackgroundEosinophilic esophagitis (EoE) is a chronic immune mediated inflammatory disorder of the esophagus. It is still unknown why children and adults present differently, and there is little evidence about why it is more common in men than women.ObjectiveOur aim was to synthesize published and unpublished esophageal bulk RNA-sequencing (RNA-seq) data to gain novel insights into the pathobiology of EoE and...

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