Article

Mutations in Homologous Recombination Repair Genes in Colorectal Cancer Are Associated With Favorable Response to Immune Checkpoint Inhibitors

2022-03-07

Abstract excerpt

<title>Abstract</title> <p><bold><italic>Background:</italic> </bold>A small proportion of patients with metastatic colorectal cancer (CRC) who might respond well to immune checkpoint inhibitors (ICIs) can be identified based on the biomarker of high microsatellite instability. Genes involved in homologous recombination repair (HRR) have been linked to response to such therapy. <bold><italic>Methods:</italic></bo...

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Literature Corpus work: 8163e907-5f5f-5191-948e-90fdf5dbe64b
DOI: 10.21203/rs.3.rs-1337915/v1

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