Article

Somatic mutations in homologous recombination pathway predict favorable prognosis after immunotherapy across multiple cancer types

2021-06-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Homologous recombination (HR) pathway was recently implicated in modifying the tumor immune microenvironment and thus might serve as a candidate biomarker of immune checkpoint inhibitor (ICI) treatment. We aimed to comprehensively explore the clinical and molecular significance of HR mutations in ICI treatment across multiple cancer types.<bold>Methods:</bold> W...

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Literature Corpus work: 7fe85555-3508-5965-90aa-833ca60703aa
DOI: 10.21203/rs.3.rs-556047/v1

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