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The next bastion to be conquered in immunotherapy: microsatellite stable colorectal cancer

22 Dec 2023

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide, and its incidence continues to rise, particularly in developing countries. The advent of immune checkpoint inhibitors (ICIs) has represented a significant advancement in CRC treatment. Deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H) serves as a biomarker for immunotherapy, with dMMR/MSI-H CRC...

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PMID: 38187388
DOI: 10.3389/fimmu.2023.1298524

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