Article

Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling

2020-04-18

Abstract excerpt

Organelles in eukaryotic cells are compartmentalized to carry out different functions, and require specific mechanisms governing their coordination. Two of these organelles, the lysosome and the endoplasmic reticulum (ER), play crucial roles in regulating cellular homeostasis and organismal health. The lysosome contains various enzymes devoted to the hydrolysis of specific substrates, and dysfunctions of these hyd...

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Literature Corpus work: 80fbe943-7124-557d-880b-aea4f7372db5
DOI: 10.1101/2020.04.18.048561

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