Article
Sorting Nexins in Protein Homeostasis
2020-11-06
Abstract excerpt
Sorting nexins (SNXs) are a highly conserved membrane-associated protein family that plays a role in regulating protein homeostasis. This family of proteins is unified by their characteristic phox (PX) phosphoinositides binding domain. Along with binding to membranes, this family of SNXs also comprises a diverse array of protein-protein interaction motifs that are required for cellular sorting and protein traffick...
Topics
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- Adaptor Proteins, Signal Transducing
- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Calcium signaling and nucleotide metabolism
- Cellular transport and secretion
- Endoplasmic Reticulum Stress and Disease
- Parkinson's Disease Mechanisms and Treatments
- Ubiquitin and proteasome pathways
Identifiers and source
- Literature Corpus work
- c57c22fb-a021-5bbb-9170-503a706520e8
- DOI
- 10.20944/preprints202011.0241.v1
