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Article

WDR41 supports lysosomal response to changes in amino acid availability.

Molecular biology of the cell - 1 Sept 2018

Amick Joseph, Tharkeshwar Arun Kumar, Amaya Catherine, Ferguson Shawn M

Abstract excerpt

C9orf72 mutations are a major cause of amyotrophic lateral sclerosis and frontotemporal dementia. The C9orf72 protein undergoes regulated recruitment to lysosomes and has been broadly implicated in control of lysosome homeostasis. However, although evidence strongly supports an important function for C9orf72 at lysosomes, little is known about the lysosome recruitment mechanism. In this study, we identify an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29995611
DOI: 10.1091/mbc.E17-12-0703
PMCID: PMC6249801

Genes

SMCR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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