Article

Global regulatory transitions at core promoters demarcate the mammalian germline cycle

2020-10-30

Abstract excerpt

Core promoters integrate regulatory inputs of genes 1–3 . Global dynamics of promoter usage can reveal systemic changes in how genomic sequence is interpreted by the cell 4 Here we report the first analysis of promoter dynamics and code switching in the mammalian germ line, characterising the full cycle of transitions from embryonic stem cells through germline, oogenesis, and zygotic genome activation. Using Sup...

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Literature Corpus work: 80e50e44-6aa8-57f1-b9d9-f655e63568b6
DOI: 10.1101/2020.10.30.361865

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