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The single-cell chromatin accessibility landscape in mouse perinatal testis development

25 Apr 2023

Abstract excerpt

Spermatogenesis depends on an orchestrated series of developing events in germ cells and full maturation of the somatic microenvironment. To date, the majority of efforts to study cellular heterogeneity in testis has been focused on single-cell gene expression rather than the chromatin landscape shaping gene expression. To advance our understanding of the regulatory programs underlying testicular cell types, we...

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PMID: 37096870
DOI: 10.7554/elife.75624

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