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Article

Heterotachy in mammalian promoter evolution.

PLoS genetics - 1 Apr 2006

Taylor Martin S, Kai Chikatoshi, Kawai Jun, Carninci Piero, Hayashizaki Yoshihide, Semple Colin A M

Abstract excerpt

We have surveyed the evolutionary trends of mammalian promoters and upstream sequences, utilising large sets of experimentally supported transcription start sites (TSSs). With 30,969 well-defined TSSs from mouse and 26,341 from human, there are sufficient numbers to draw statistically meaningful conclusions and to consider differences between promoter types. Unlike previous smaller studies, we have considered the...

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Identifiers

PMID: 16683025
DOI: 10.1371/journal.pgen.0020030
PMCID: PMC1449885

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