Article

Single nucleus multi-omics regulatory atlas of the murine pituitary

2020-06-07

Abstract excerpt

The pituitary regulates growth, reproduction and other endocrine systems. To investigate transcriptional network epigenetic mechanisms, we generated paired single nucleus (sn) transcriptome and chromatin accessibility profiles in single mouse pituitaries and genome-wide sn methylation datasets. Our analysis provided insight into cell type epigenetics, regulatory circuit and gene control mechanisms. Latent variable...

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Literature Corpus work: cde67a0a-b599-5179-bf08-c57ff594733b
DOI: 10.1101/2020.06.06.138024

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