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ER-stress signaling and Alzheimer’s proteins adjust the quality of human protein synthesis

2026-02-24

Abstract excerpt

Proteostasis is the balance of protein synthesis, protein maintenance and protein degradation. Proteostasis is disturbed in neurodegenerative disorders like Alzheimer’s disease (AD) of the aging human body. Protein synthesis by the ribosome is the most error-prone process in gene expression. If and how the error-rate of protein synthesis is regulated during human aging and contributes to AD is unknown. Here we sho...

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Literature Corpus work
80d55d79-d556-53ee-af2b-6e72dcdf4c07
DOI
10.64898/2026.02.23.707382
Open publication

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ER-stress signaling and Alzheimer’s proteins adjust the quality of human protein synthesisDOI 10.64898/2026.02.23.707382
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