Article

Unravelling the progression of unfolded protein Rresponse in a model system of familial Alzheimer's disease

2015-01-01

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia disorders and, yet, there is no preventative or curative treatment. It is associated with the progressive loss of memory and cognition and clinically divided into sporadic and familial forms. Familial Alzheimer's disease (FAD) has predominantly a genetic predisposition with inherited mutations in the amyloid-β precursor protein (APP) and presinilin genes...

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Literature Corpus work: dc2cacaf-ee9a-5a58-a4dc-eafac86f3442
DOI: 10.25560/42359

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