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PRDM9 and an Epidemic of Gene Conversion and Non-Homologous Recombination among <i>Alu</i> Elements in Ancestral Gorillas

2017-12-31

Abstract excerpt

We performed a genome-wide scan for recombination-mediated interlocus gene conversion and deletion events among a set of orthologous Alu loci in the Great Apes, and were surprised to discover an extreme excess of such events in the gorilla lineage versus other lineages. Gorilla events, but not events in other Great Apes, are strongly associated with a 15 bp motif commonly found in Alu sequences. This result is c...

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Literature Corpus work
80b88957-a44b-5d29-aeaa-7bfafc5a5847
DOI
10.1101/241356
Open publication

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PRDM9 and an Epidemic of Gene Conversion and Non-Homologous Recombination among <i>Alu</i> Elements in Ancestral GorillasDOI 10.1101/241356
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