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Article

The role of gene conversion in preserving rearrangement hotspots in the human genome.

Trends in genetics : TIG - 1 Oct 2013

Fawcett Jeffrey A, Innan Hideki

Abstract excerpt

Hotspots of non-allelic homologous recombination (NAHR) have a crucial role in creating genetic diversity and are also associated with dozens of genomic disorders. Recent studies suggest that many human NAHR hotspots have been preserved throughout the evolution of primates. NAHR hotspots are likely to remain active as long as the segmental duplications (SDs) promoting NAHR retain sufficient similarity. Here, we...

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Identifiers

PMID: 23953668
DOI: 10.1016/j.tig.2013.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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