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Article

Germline methylation patterns determine the distribution of recombination events in the dog genome.

Genome biology and evolution - 19 Dec 2014

Berglund Jonas, Quilez Javier, Arndt Peter F, Webster Matthew T

Abstract excerpt

The positive-regulatory domain containing nine gene, PRDM9, which strongly associates with the location of recombination events in several vertebrates, is inferred to be inactive in the dog genome. Here, we address several questions regarding the control of recombination and its influence on genome evolution in dogs. First, we address whether the association between CpG islands (CGIs) and recombination hotspots...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25527838
DOI: 10.1093/gbe/evu282
PMCID: PMC4350167

Genes

PRDM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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