Article

Sex differences in PRDM9-independent fine-scale recombination patterns

2026-06-22

Abstract excerpt

Meiotic recombination rates exhibit strong, fine-scale variation along the genome of many eukaryotes. In some animals, including humans, the protein PRDM9 directs recombination toward so-called recombination hotspots. However, in birds and dogs, which have lost PRDM9, hotspots generally occur in promoter sequences called CpG islands. Furthermore, in many species, recombination rates and patterns differ between the...

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Literature Corpus work: b046192a-8645-5124-9c75-d617df7a1574
DOI: 10.64898/2026.06.19.733336

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