Article

Insights into gene conversion and crossing-over processes from long-read sequencing of human, chimpanzee and gorilla testes and sperm

2024-07-06

Abstract excerpt

Homologous recombination rearranges genetic information during meiosis to generate new combinations of variants. Recombination also causes new mutations, affects the GC content of the genome and reduces selective interference. Here, we use HiFi long-read sequencing to directly detect crossover and gene conversion events from switches between the two haplotypes along single HiFi-reads from testis tissue of humans,...

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Literature Corpus work: b74f724c-5403-572d-ab1a-e70828d0249e
DOI: 10.1101/2024.07.05.601967

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