Article
Alu recombination-mediated structural deletions in the chimpanzee genome.
PLoS genetics - 1 Oct 2007
Han Kyudong, Lee Jungnam, Meyer Thomas J, Wang Jianxin, Sen Shurjo K, Srikanta Deepa, Liang Ping, Batzer Mark A
Abstract excerpt
With more than 1.2 million copies, Alu elements are one of the most important sources of structural variation in primate genomes. Here, we compare the chimpanzee and human genomes to determine the extent of Alu recombination-mediated deletion (ARMD) in the chimpanzee genome since the divergence of the chimpanzee and human lineages ( approximately 6 million y ago). Combining computational data analysis and...
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