Article

CTCF-anchored chromatin loop dynamics during human meiosis

2024-03-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> During meiosis, the mammalian genome is organised within chromatin loops, which facilitate synapsis, crossing over and chromosome segregation, setting the stage for recombination events and the generation of genetic diversity. Chromatin looping is thought to play a major role in the establishment of cross overs during prophase I of meiosis, in diploid early primary spermatoc...

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Literature Corpus work: 804d36ac-7e71-5e05-8848-b2bfd0eb1423
DOI: 10.1101/2024.02.29.582729

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