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Somatic mutations in homologous recombination pathway predict favourable prognosis after immunotherapy across multiple cancer types

1 Dec 2021

Abstract excerpt

Homologous recombination (HR) pathway was recently implicated in modifying the antitumour response and thus might serve as a biomarker of immune checkpoint inhibitor (ICI) treatment.1 Thus, this study aims to comprehensively explore the clinical and molecular significance of HR mutations in ICI treatment across multiple cancer types. The details of data and methods were descripted in Table S1 and supplementary...

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PMID: 34923755
DOI: 10.1002/ctm2.619

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