Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative analysis of homologous recombination repair patterns unveils prognostic signatures and immunotherapeutic insights in breast cancer.

Journal of applied genetics - 1 Dec 2024

Li Yan-Shuang, Jiang Hong-Chuan

Abstract excerpt

Globally, breast cancer (BC) is the leading cause of female death and morbidity. Homologous recombination repair (HRR) is critical in BC. However, the prognostic role and immunotherapy response of HRR in BC remains to be clarified. Firstly, we identified HRR types in BC samples from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) dataset (GSE42568) based on 65 HRR genes (HRRGs). A differentially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Immunotherapy

Share to Mutation

Share to Prognosis

Share to Recombinational DNA Repair

Source

Open in PubMed Open full text

Identifiers

PMID: 38478326
DOI: 10.1007/s13353-024-00848-1
PMCID: PMC11561031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative analysis of homologous recombination repair patterns unveils prognostic signatures and immunotherapeutic insights in breast cancer.PMID 38478326Read ↗

Integrative Analysis of Homologous Recombination Repair Patterns Unveils Prognostic Signatures and Immunotherapeutic Insights in Breast CancerSemantic proximity Read ↗

Homologous recombination deficiency reflects the heterogeneity and monitoring treatment response for patients with breast cancer.Semantic proximity Read ↗

Multi-omics analyses unravel DNA damage repair-related clusters in breast cancer with experimental validationSemantic proximity Read ↗

Prognostic analysis of patients with breast cancer based on tumor mutational burden and DNA damage repair genesSemantic proximity Read ↗

Homologous repair deficiency score for identifying breast cancers with defective DNA damage responseSemantic proximity Read ↗

Identification of a novel gene signature with DDR and EMT difunctionalities for predicting prognosis, immune activity, and drug response in breast cancerSemantic proximity Read ↗

Multiomics analysis of homologous recombination deficiency across cancer types.Semantic proximity Read ↗

Prognostic Analysis of Patients with Breast Cancer Based on Tumor Mutational Burden, DNA Damage Repair Genes, and Immune InfiltrationSemantic proximity Read ↗

Construction of a DNA damage repair gene signature for predicting prognosis and immune response in breast cancerSemantic proximity Read ↗

Identification of a combined apoptosis and hypoxia gene signature for predicting prognosis and immune infiltration in breast cancerSemantic proximity Read ↗

Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancerSemantic proximity Read ↗

Pan-cancer analysis reveals homologous recombination deficiency score as a predictive marker for immunotherapy responders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.