Article

Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in <i>Pseudomonas aeruginosa</i>

2017-10-02

Abstract excerpt

<h4>Background and objectives</h4> Treatments that inhibit the expression or functioning of bacterial virulence factors hold great promise to be both effective and exert weaker selection for resistance than conventional antibiotics. However, the evolutionary robustness argument, based on the idea that anti-virulence treatments disarm rather than kill pathogens, is controversial. Here we probe the evolutionary rob...

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Literature Corpus work: 7f9e7b1a-92bd-5d74-9eab-4ecfe62614d9
DOI: 10.1101/195974

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