When is a bacterial “virulence factor” really virulent?

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial traits that contribute to disease are termed ‘virulence factors’ and there is much interest in therapeutic approaches that disrupt such traits. However, ecological theory predicts disease severity to be multifactorial and context dependent, which might complicate our efforts to identify the most generally important virulence factors. Here, we use meta-analysis to quantify disease outco...

Topics

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• Adaptation, Physiological
• Anti-Bacterial Agents
• Bacteria
• Bacterial Infections
• Drug Resistance, Bacterial
• Evolution and Genetic Dynamics
• Insect symbiosis and bacterial influences
• Mathematical and Theoretical Epidemiology and Ecology Models

Identifiers and source

Literature Corpus work

a824269f-918a-501a-9339-73a4842dcd99

DOI

10.1101/061317