Article

Shared loci but distinct variants underlie genetic architecture of allergic diseases

2025-06-07

Abstract excerpt

Asthma, allergic rhinitis, and atopic dermatitis are common, complex traits that are frequently co-morbid and have strong genetic correlation. However, the extent to which genome-wide genetic correlation between traits reflects shared causal variants or risk genes remains unclear. To address this question, we used functional fine-mapping. We generated genomic annotations from primary cells treated with immunomodul...

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Literature Corpus work: 7f7b8bfc-3b91-558e-be75-ab7b4dcdb9bb
DOI: 10.1101/2025.06.06.25329154

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