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Engineered <i>Acinetobacter baylyi</i> ADP1-ISx cells are sensitive DNA biosensors for antibiotic resistance genes and a fungal pathogen of bats

2025-05-18

Abstract excerpt

Naturally competent bacteria can be engineered into platforms for detecting environmental DNA. This capability could be used to monitor the spread of pathogens, invasive species, and resistance genes, among other applications. Here, we create Acinetobacter baylyi ADP1-ISx biosensors that detect specific target DNA sequences through natural transformation. We tested strains with DNA sensors that consisted of eithe...

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Literature Corpus work
457e6ae8-5150-58da-a8bd-06a3c132f359
DOI
10.1101/2025.05.17.654686
Open publication

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Engineered <i>Acinetobacter baylyi</i> ADP1-ISx cells are sensitive DNA biosensors for antibiotic resistance genes and a fungal pathogen of batsDOI 10.1101/2025.05.17.654686
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