Article

Impact of Genetic Risk Factors on Coronary Heart Disease Risk Across the Age Spectrum in Three Major Race/Ethnicity Groups in the United States

2025-11-15

Abstract excerpt

<h4>Background</h4> Measures of genetic predisposition can improve prediction of risk of cardiometabolic diseases but more data is needed in groups under-represented in genomics research. In this study, we investigated the impact of genetic risk factors for coronary heart disease (CHD) - polygenic risk, monogenic risk [in the form of familial hypercholesterolemia (FH)], and family history (FamHx) - on CHD risk es...

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Literature Corpus work: 7f359f6e-bc15-5295-8776-e0194c0370e1
DOI: 10.1101/2025.11.10.25339939

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