Article

<i>mps1</i> and <i>mad</i> mutations reduce <i>Cryptococcus neoformans</i> titan cell viability

2023-04-09

Abstract excerpt

Cryptococcus neoformans is an opportunistic, human fungal pathogen which undergoes fascinating switches in cell cycle control and ploidy when it encounters stressful environments such as the human lung. Here we carry out a mechanistic analysis of the spindle assembly checkpoint (SAC) which regulates the metaphase to anaphase transition, focusing on Mps1 kinase and the downstream checkpoint components Mad1 and Mad2...

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Literature Corpus work: 7f03251e-b2f6-596e-bee8-fc2dd0e6e5ea
DOI: 10.1101/2023.04.09.536157

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