Article
The cyclin Cln1 controls polyploid titan cell formation following a stress-induced G2 arrest in <i>Cryptococcus</i>
2021-08-25
Abstract excerpt
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response to the host lung environment that are critical for host adaptation and subsequent disease. We analyzed the in vivo and in vitro cell cycles to identify key aspects of the C. neoformans cell cycle that are important for the formation of titan cells. We identified unbudded 2C cells, referred to as a G2 arrest, produced both...
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Identifiers and source
- Literature Corpus work
- 9b0bf351-d970-577d-b42d-2a995ff383bc
- DOI
- 10.1101/2021.08.24.457603