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The role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in <i>Mycobacterium tuberculosis</i> complex

2021-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Antibiotic resistance among bacterial pathogens poses a major global health threat. M. tuberculosis complex (MTBC) is estimated to have the highest resistance rates of any pathogen globally. Given the slow growth rate and the need for a biosafety level 3 laboratory, the only realistic avenue to scale up drug-susceptibility testing (DST) for this pathogen is to rely on genotypic techniques. This...

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Literature Corpus work
7ec0c406-7a72-5b74-b67a-7ca33fcab4f2
DOI
10.1101/2021.05.07.443178
Open publication

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The role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in <i>Mycobacterium tuberculosis</i> complexDOI 10.1101/2021.05.07.443178
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