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Article

Systematic identification of genetic influences on methylation across the human life course.

Genome biology - 31 Mar 2016

Gaunt Tom R, Shihab Hashem A, Hemani Gibran, Min Josine L, Woodward Geoff, Lyttleton Oliver, Zheng Jie, Duggirala Aparna, McArdle Wendy L, Ho Karen, Ring Susan M, Evans David M, Davey Smith George, Relton Caroline L

Abstract excerpt

BACKGROUND: The influence of genetic variation on complex diseases is potentially mediated through a range of highly dynamic epigenetic processes exhibiting temporal variation during development and later life. Here we present a catalogue of the genetic influences on DNA methylation (methylation quantitative trait loci (mQTL)) at five different life stages in human blood: children at birth, childhood, adolescence...

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Source

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Identifiers

PMID: 27036880
DOI: 10.1186/s13059-016-0926-z
PMCID: PMC4818469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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