Article

High-throughput complement component 4 genomic sequence analysis with C4Investigator

2023-07-19

Abstract excerpt

The complement component 4 gene locus, composed of the C4A and C4B genes and located on chromosome 6, encodes for C4 protein, a key intermediate in the classical and lectin pathways of the complement system. The complement system is an important modulator of immune system activity and is also involved in the clearance of immune complexes and cellular debris. The C4 gene locus exhibits copy number variation, wit...

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Literature Corpus work: 7e82ce3c-2f65-584d-af05-98a934cf59ee
DOI: 10.1101/2023.07.18.549551

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