Article

Computational Analysis of crRNA to Regulate hsa-miR-301b-3p and hsa-miR-21 related to metastasis and cell proliferation in acute myeloid leukemia (AML) using CRISPR/C2c2

2023-03-13

Abstract excerpt

<h4>Background: </h4> Myeloid or lymphoid progenitors in the bone marrow can develop into leukemia, which is clonal cancer. Acute myeloid leukemia (AML) developed as a result of somatic mutations in the precursor cells of the myeloid lineage along with transcriptome dysregulation of bone marrow infiltration, which resulted in the generation of immature myeloid cells (blasts) and disruption of normal hematopoiesis....

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Literature Corpus work: 7e28eb9f-1816-5027-ac8c-4ce4b8a7a968
DOI: 10.21203/rs.3.rs-2583636/v1

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