Article

Six novel nsSNPs affect <i>RUNX1</i> gene may leading to Acute Myeloid Leukemia (AML) using Bioinformatics approach

2023-06-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> RUNX1 is one of the most frequently mutated genes in human AMLs, most of RUNX1 mutations in acute myeloid leukemia (AML) are missense or deletion-truncation and behave as loss-of-function mutations. The molecular consequences of cancer associated mutations in Acute myeloid leukemia (AML) linked factors are not very well understood. Here, we recognize possible pathogenic SNP...

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Literature Corpus work: 61a35233-9c19-5eaf-9f5c-7cc5f6a2757e
DOI: 10.1101/2023.06.26.546458

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