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MicroRNAs in Myeloid Hematological Malignancies

10 Jul 2015

Abstract excerpt

MicroRNAs are 19-24 nucleotides noncoding RNAs which silence modulate the expression of target genes by binding to the messenger RNAs. Myeloid malignancies include a broad spectrum of acute and chronic disorders originating from from the clonal transformation of a hematopoietic stem cell. Specific genetic abnormalities may define myeloid malignancies, such as translocation t(9;22) that represent the hallmark of...

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PMID: 27047254
DOI: 10.2174/138920291605150710122815

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