Article

Drugs targeting microRNAs that regulate DNA damage sensing and repair mechanisms: <i>A computational drug discovery approach</i>

2024-06-22

Abstract excerpt

<h4> ABSTRACT </h4> DNA damage-sensing (DDS) and DNA damage-repair (DDR) mechanisms are essential for the fidelity of genetic information transmission. Failure to accomplish an effective DDS/DDR mechanism can lead to cell death or otherwise to cell transformation and cancer development. microRNAs (miRs) are short noncoding RNAs that primarily function as micromanagers of gene expression. Herein, we aimed to inve...

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Literature Corpus work: 70d3dc01-e8f2-5119-8db1-e3b59e748823
DOI: 10.1101/2024.06.18.599590

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