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Small RNA activation of CDH13 expression overcome BCR-ABL1-independent imatinib-resistance and their signaling pathway studies in chronic myeloid leukemia

2024-02-20

Abstract excerpt

<title>Abstract</title> <p>BCR-ABL1-independent resistance to imatinib has no effective treatment due to its complexity and diversity. We previously reported that the CDH13 oncogene was expressed at low levels in BCR-ABL1-independent resistant CML cell lines. However, its effects on CML resistant cells and mechanisms remain unknown. This study investigated the effects of saRNA-based CDH13 activation on BCR-ABL1-i...

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Literature Corpus work
8ebcd940-e7fa-5a06-ab74-7a9b4265a801
DOI
10.21203/rs.3.rs-3402305/v1
Open publication

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Small RNA activation of CDH13 expression overcome BCR-ABL1-independent imatinib-resistance and their signaling pathway studies in chronic myeloid leukemiaDOI 10.21203/rs.3.rs-3402305/v1
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